The Federal Drug Administration recently recommended that the bedtime dose for Zolpidem (Ambien) be reduced, citing growing concerns over the drug's side effects.
It turns out that the active ingredient in zolpidem takes the body far longer to process than originally thought, with women's bodies taking longer than men's.
The recommended dose for women is being halved from 10mg to 5mg for instant release products such as Ambien, Edluar and Zolpimist and from 12.5mg to 6.25mg for extended release products such as Ambien CR.
The FDA wants to see labeling on the drug recommend the same lower doses for men, too.
In recommending a lower dose, the FDA specifically mentions concerns over impaired driving and daytime grogginess the following day - side effects that are all to common, as our insomnia support forums can testify.
Last updated: March 27, 2013